- Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
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Xiang-Quan Xie, Kui-Cheng Zheng, Bing-Shan Wu, Tie-Hui Chen, Shan-Rong Lai, Zai-Sheng Lin, Kazuo Aoki
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J Prev Med Public Health. 2014;47(5):281-287. Published online September 12, 2014
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DOI: https://doi.org/10.3961/jpmph.14.018
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In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. Methods: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. Results: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. Conclusions: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do.
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Citations
Citations to this article as recorded by  - Changing trends of clinicopathologic features and survival duration after surgery for gastric cancer in Northeast China
Zhao Zhai, Zi-Yu Zhu, Xi-Liang Cong, Bang-Ling Han, Jia-Liang Gao, Xin Yin, Yu Zhang, Sheng-Han Lou, Tian-Yi Fang, Yi-Min Wang, Chun-Feng Li, Xue-Feng Yu, Yan Ma, Ying-Wei Xue
World Journal of Gastrointestinal Oncology.2020; 12(10): 1119. CrossRef - Poor expression of microRNA‐135b results in the inhibition of cisplatin resistance and proliferation and induces the apoptosis of gastric cancer cells through MST1‐mediated MAPK signaling pathway
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Journal of Clinical Laboratory Analysis.2018;[Epub] CrossRef
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